Xgeva Solution for Injection is a medicine used in the treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. It makes the bones strong and reduce the risk of fractures. Xgeva Solution for Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. To make it more effective, take adequate amount of calcium and vitamin D supplements while on treatment with this medicine. Some common side effects of this medicine include pain in extremity, musculoskeletal pain, nerve pain, urinary tract infection, constipation, and rash. Talk to your doctor if any of these side effects does not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking it, let your doctor know of all the other medicines you are taking. It is important for pregnant and breastfeeding mothers to ask the advice of their doctors before using this medicine.

• Pain in extremities
• Nerve pain
• Constipation
• Rash
• Urinary tract infection

If you miss a dose of Xgeva Solution for Injection, please consult your doctor.

• Q. Q. How long can you stay on Xgeva Solution for Injection??
  Ans: There is no optimal duration of treatment of osteoporosis with Xgeva Solution for Injection. The patient’s response and tolerability to the medicine is continuously monitored through periodic assessments, especially after 5 years of use of Xgeva Solution for Injection. Depending on this, the duration of taking Xgeva Solution for Injection is decided.
• Q. Q. Does Xgeva Solution for Injection cause hair loss??
  Ans: Yes, hair loss is a common side effect of Xgeva Solution for Injection though it does not affect everyone. Discuss with your doctor if you have concerns regarding your hair loss.
• Q. Q. Is Xgeva Solution for Injection a chemotherapy drug??
  Ans: Xgeva Solution for Injection is not a chemotherapy drug. It is a protein (monoclonal antibody) that interferes with the action of another protein in order to treat bone loss and osteoporosis. Treatment with Xgeva Solution for Injection makes the bones stronger and less likely to break.
• Q. Q. How is Xgeva Solution for Injection given and how often??
  Ans: Xgeva Solution for Injection is available as an injection and is given by a healthcare professional. It is given once in 6 months. Your doctor may also advise you to take calcium and vitamin D while taking Xgeva Solution for Injection.
• Q. Q. Can Xgeva Solution for Injection be taken during pregnancy??
  Ans: No, pregnant women should not take Xgeva Solution for Injection. You must use an effective method of birth control during and for at least 5 months after the last dose of Xgeva Solution for Injection if you can become pregnant.
• Q. Q. How should Xgeva Solution for Injection be stored??
  Ans: Xgeva Solution for Injection should be stored in a refrigerator at 36°F to 46°F (2°C to 8°C) in the original carton. Warm temperatures can make it ineffective, and therefore proper storage is necessary. When you remove it from the refrigerator, keep it at room temperature [up to 77°F (25°C)] in the original carton and use it within 14 days.
• Q. Q. Does Xgeva Solution for Injection cause osteonecrosis of the jaw??
  Ans: Osteonecrosis is a rare side effect of Xgeva Solution for Injection. It refers to the damage caused to the bone of jaw. To avoid this, you should maintain good oral hygiene and receive routine dental check ups while taking Xgeva Solution for Injection. Contact your doctor and dentist immediately if you experience any problems with your mouth or teeth such as loose teeth, discharge, pain or swelling, or non-healing of sores. These could be signs of osteonecrosis of jaw.

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