Vertex Plus 650mg/5mg Tablet is a combination of two medicines used in the treatment of migraine. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraine. Vertex Plus 650mg/5mg Tablet can be taken with or without food. Take it in the dose and duration prescribed by your doctor. You should keep taking the medicine even if you feel better until the doctor says it is alright to stop using it. Using of this medicine may cause few common side effects like dry mouth, constipation, weight gain, and decreased blood pressure. If you experience any such side effects that does not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using the medicine, you should tell your doctor if you have any other medical conditions or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholic or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

• Constipation
• Weight gain
• Increased prolactin level in blood
• Decreased blood pressure
• Sedation
• Urinary retention

If you miss a dose of Vertex Plus 650mg/5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

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