Ujvira 100mg Injection is used in the treatment of breast and stomach cancer. It works by killing the cancer cells by inhibiting HER2 (human epidermal growth factor receptor protein). Ujvira 100mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include nausea, headache, rash, insomnia, and infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels. You must have to inform your doctor if you experience breathlessness, cough, shivering, swelling of legs and arm. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

• Chills
• Common cold
• Cough
• Decreased blood cells (red cells, white cells, and platelets)
• Diarrhea
• Fatigue
• Fever
• Headache
• Heart failure
• Infection
• Insomnia (difficulty in sleeping)
• Mucosal inflammation
• Nausea
• Rash
• Stomatitis (Inflammation of the mouth)
• Taste change
• Upper respiratory tract infection
• Weight loss

If you miss a dose of Ujvira 100mg Injection, please consult your doctor.

Chemical Class::Monoclonal antibody (mAb)|Habit Forming::No|Therapeutic Class::ANTI NEOPLASTICS|Action Class::HER2/neu (ErbB2) Inhibitor- Monoclonal antibody

• Q. Q. What are the serious side effects of Ujvira 100mg Injection??
  Ans: There are various side effects related to Ujvira 100mg Injection such as sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, and other unusual bruising or bleeding. One can also experience stomach pain, seizures, hallucinations, muscle cramps, and spasms. Along with that, nausea or vomiting, loss of appetite, fatigue, rapid heart beat, discoloration of urine; decreased amount of urine, difficulty in urinating, pain when urinating, and other signs of infection can also be observed with the use of Ujvira 100mg Injection. You should call your doctor immediately if you notice any such symptoms.
• Q. Q. How long after Ujvira 100mg Injection therapy can I get pregnant??
  Ans: Women of child-bearing age should use effective contraception during Ujvira 100mg Injection therapy and for 7 months after completing the treatment. You can plan your pregnancy after 7 months of treatment with Ujvira 100mg Injection.
• Q. Q. How long should Ujvira 100mg Injection be taken??
  Ans: Patients with early breast cancer should take Ujvira 100mg Injection for 1 year or until disease recurs, whichever occurs first. It is not advised to extend the treatment beyond 1 year in patients of early breast cancer.
• Q. Q. Is fasting required before administering Ujvira 100mg Injection? ?
  Ans: No, fasting is not required before administering Ujvira 100mg Injection. It should be given under the guidance of a doctor who is experienced in giving cancer chemotherapy and should be given only by a healthcare professional.
• Q. Q. How is Ujvira 100mg Injection given, intravenously or intramuscularly??
  Ans: There are 2 different formulations available for administration of Ujvira 100mg Injection, one is given as an infusion into a vein (intravenous infusion) and the other is given as an injection under the skin (subcutaneous injection). It is important to check the product labels to ensure that the correct formulation is being given as prescribed. Ujvira 100mg Injection intravenous formulation is not for subcutaneous use and should be given as an intravenous infusion only. Your doctor may consider switching your Ujvira 100mg Injection intravenous treatment to Ujvira 100mg Injection subcutaneous treatment (and vice versa) if considered appropriate for you.
• Q. Q. Can Ujvira 100mg Injection be given to HER2 negative cancer patients??
  Ans: No, Ujvira 100mg Injection cannot be given in patients with HER2 negative cancer cells. Ujvira 100mg Injection belongs to class of monoclonal antibody. It binds selectively to a protein called human epidermal growth factor receptor 2 (HER2). HER2 is found, in large amounts, on the surface of some cancer cells. When Ujvira 100mg Injection binds to HER2, it stops the growth and spread of the cancer cells. Therefore, it is only effective in HER2 positive patients (in which HER2 is present) and will not be beneficial for HER2 negative patients (in which HER2 is not present).
• Q. Q. Why has my doctor advised for investigations of heart??
  Ans: Ujvira 100mg Injection when used with anthracycline class of anti-cancer medicines (eg doxorubicin) may adversely affect your heart. Hence, your doctor needs to check the health of your heart initially before starting treatment and during treatment.
• Q. Q. How frequently heart investigations are required??
  Ans: Heart investigations should be performed at the starting of the treatment. It should be repeated every 3 months during treatment and every 6 months after the discontinuation of treatment until 24 months from the last administration of Ujvira 100mg Injection. Those patients who already have heart-related problems will require investigations every 12 weeks.

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