Ugesic Sublingual tablet is a pain-relieving medicine. It is used to treat moderate to severe pain in conditions such as osteoarthritis and rheumatoid arthritis. It helps relieve pain and swelling in the joints and muscles. It may also be used after a dental surgery. Ugesic Sublingual tablet should be taken with food. This will prevent you from getting an upset stomach. The dose and duration will depend on what you are taking it for and how well it helps your symptoms. Take it exactly as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. The most common side effects of this medicine include mild vomiting, stomach pain, nausea, indigestion, and diarrhea. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine. Pregnant and breastfeeding mothers should consult their doctors before using the medicine.

• Stomach pain
• Nausea
• Headache
• Dizziness

If you miss a dose of Ugesic Sublingual tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class::Enolic acid Derivatives|Habit Forming::No|Therapeutic Class::PAIN ANALGESICS|Action Class::NSAID's- Non-Selective COX 1&2 Inhibitors (enolic acids)

• Q. Q. What is the difference between Ugesic Sublingual tablet and diclofenac??
  Ans: Both Ugesic Sublingual tablet and diclofenac are pain killers. However, piroxicam is a non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain) inhibitor whereas diclofenac has a bit more selectivity to a COX-2 enzyme. This selectivity of diclofenac is supposed to decrease the side effects as compared to Ugesic Sublingual tablet.
• Q. Q. What is the difference between Ugesic Sublingual tablet and naproxen??
  Ans: Both Ugesic Sublingual tablet and naproxen are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, gastric side effects are lesser with naproxen as compared to Ugesic Sublingual tablet.
• Q. Q. What is the difference between Ugesic Sublingual tablet and meloxicam??
  Ans: Both Ugesic Sublingual tablet and meloxicam are pain killers. Both are non-selective COX (cyclooxygenase - an enzyme responsible for inflammation and pain). Research studies have shown both are equally effective. However, acute gastric side effects are lesser with meloxicam as compared to Ugesic Sublingual tablet.
• Q. Q. What is the difference between Ugesic Sublingual tablet and ketoprofen??
  Ans: Both Ugesic Sublingual tablet and ketoprofen are pain killers. Both are non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain). Research studies have shown ketoprofen topical gel is better and effective as compared to Ugesic Sublingual tablet. Ketoprofen gel also showed excellent tolerability.
• Q. Q. What is the difference between Ugesic Sublingual tablet and tramadol??
  Ans: Ugesic Sublingual tablet is a COX (cyclooxygenase -an enzyme responsible for inflammation and pain) whereas Tramadol is a narcotic-like painkiller. Tramadol is a habit forming medicine.
• Q. Q. What is the difference between Ugesic Sublingual tablet and nimesulide??
  Ans: Both Ugesic Sublingual tablet and nimesulide are pain killers. However, Ugesic Sublingual tablet is a non-selective COX (cyclooxygenase -an enzyme responsible for inflammation and pain) inhibitor whereas nimesulide is selective to the COX-2 enzyme. This selectivity of nimesulide is supposed to decrease the side effects as compared to piroxicam. It should not be used in children below 12 years of age.
• Q. Q. Can Ugesic Sublingual tablet be used in the treatment of chikungunya??
  Ans: Usually, the platelet count does not dip in cases of chikungunya and painkillers like piroxicam can lead to the risk of increased bleeding tendency. So refrain from taking Ugesic Sublingual tablet or any painkiller in the case of any fever with joint pain. Consult your doctor before starting Ugesic Sublingual tablet.
• Q. Q. Are Ugesic Sublingual tablet and aspirin same??
  Ans: No. Ugesic Sublingual tablet and aspirin are not same. They belong to the same class of drugs known as COX (cyclooxygenase) inhibitors. They both are anti-inflammatory and analgesic.
• Q. Q. Can Ugesic Sublingual tablet be used along with dexamethasone??
  Ans: No. Ugesic Sublingual tablet should not be used with dexamethasone. They both increase each other's toxicity. There is an increased risk of GI ulceration.
• Q. Q. Can Ugesic Sublingual tablet be used with methocarbamol??
  Ans: Yes. Methocarbamol can be used with Ugesic Sublingual tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
• Q. Q. Can Ugesic Sublingual tablet be used along with paracetamol??
  Ans: Yes. Paracetamol can be used with Ugesic Sublingual tablet as no serious side effects are known. Inform your doctor before starting any of the medication.
• Q. Q. Is Ugesic Sublingual tablet a NSAID??
  Ans: Yes. Ugesic Sublingual tablet is a non-steroidal anti-inflammatory drug (NSAID).
• Q. Q. Is Ugesic Sublingual tablet a sulfa drug??
  Ans: Ugesic Sublingual tablet is a sulphur containing compound. Ugesic Sublingual tablet can cause serious adverse events in sensitive individuals. It can cause severe skin reactions like Steven Johnson Syndrome. Do inform your doctor if you have any kind of allergies.
• Q. Q. Is Ugesic Sublingual tablet a blood thinner??
  Ans: No. Ugesic Sublingual tablet is not a blood thinner. It is a pain killer. It should be avoided in a patient with a bleeding disorder.
• Q. Q. Is Ugesic Sublingual tablet a muscle relaxant??
  Ans: No. Ugesic Sublingual tablet is not a muscle relaxant. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme.
• Q. Q. Is Ugesic Sublingual tablet a narcotic??
  Ans: No. Ugesic Sublingual tablet is not a narcotic. It is a pain killer which acts on COX (cyclooxygenase -an enzyme responsible for inflammation and pain) enzyme to decrease the pain and inflammation.
• Q. Q. Can Ugesic Sublingual tablet be used in hypertension??
  Ans: No. Ugesic Sublingual tablet is not a medication to control hypertension. It is important to note that Ugesic Sublingual tablet decreases the effectiveness of the antihypertensive medication when given together. Inform your doctor if you are taking antihypertensive medications before starting Ugesic Sublingual tablet.
• Q. Q. Can Ugesic Sublingual tablet be used along with Losartan??
  Ans: No. Ugesic Sublingual tablet should not be combined with Losartan. It is important to note that Ugesic Sublingual tablet decreases the effectiveness of the antihypertensive medication like losartan when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Ugesic Sublingual tablet.
• Q. Q. Can Ugesic Sublingual tablet be used with Lisinopril??
  Ans: No. Ugesic Sublingual tablet should be avoided with lisinopril. It is important to note that piroxicam decreases the effectiveness of the antihypertensive medication like lisinopril when given together leading to failure of antihypertensive therapy. Inform your doctor if you are taking antihypertensive medications before starting Ugesic Sublingual tablet.
• Q. Q. Can Ugesic Sublingual tablet be used with calcium channel blocker??
  Ans: Yes. Ugesic Sublingual tablet can be taken with calcium channel blocker. NSAIDs have been observed to reduce the effectiveness of all antihypertensive drugs except calcium channel blockers (ref: White 2007)
• Q. Q. Can Ugesic Sublingual tablet be used with Tizanidine??
  Ans: Yes, Ugesic Sublingual tablet can be combined with tizanidine. Piroxicam is a pain killer and tizanidine is a skeletal muscle relaxant. It is used in the condition like a backache.
• Q. Q. Why is beta cyclodextrin added to Ugesic Sublingual tablet??
  Ans: Yes. Ugesic Sublingual tablet can be combined with beta-cyclodextrin. Research has shown that combining Ugesic Sublingual tablet with beta-cyclodextrin leads to faster onset of action of piroxicam and reduced gastric side effects.
• Q. Q. Are there any alternatives of Ugesic Sublingual tablet??
  Ans: Yes. There are alternatives to Ugesic Sublingual tablet. Pain killers are prescribed according to the disease condition. Consult your doctor before starting piroxicam or changing it to other medication.
• Q. Q. What are the contraindications for Ugesic Sublingual tablet??
  Ans: Contraindications to piroxicam are an allergy, bleeding tendency, duodenal/gastric/peptic ulcer, stomatitis, Systemic Lupus Erythematosus (SLE), ulcerative colitis, upper GI disease, late pregnancy, cardiac disease, hepatic impairment, renal impairment.
• Q. Q. Can Ugesic Sublingual tablet be used in the treatment of allergy??
  Ans: No. Ugesic Sublingual tablet is not a drug to treat allergy. It is a pain killer.
• Q. Q. How long does Ugesic Sublingual tablet work??
  Ans: Ugesic Sublingual tablet is a long acting drug. Once the daily dose is enough for the relief of pain but it depends from person to person as the effectiveness of piroxicam increases when given for few weeks.
• Q. Q. Can you get high by using Ugesic Sublingual tablet??
  Ans: No. Ugesic Sublingual tablet is not known to cause high. It is a non-narcotic painkiller.
• Q. Q. Can Ugesic Sublingual tablet be used to treat menstrual cramp??
  Ans: Ugesic Sublingual tablet is not approved for the treatment of menstrual cramps. Research studies have shown that piroxicam is quite effective in significantly decreasing the menstrual cramps.
• Q. Q. Can I use Ugesic Sublingual tablet for a migraine??
  Ans: Ugesic Sublingual tablet is not approved for the treatment of migraine. Research studies have shown that Ugesic Sublingual tablet is effective in significantly decreasing the pain associated with migraine without aura.
• Q. Q. Is Ugesic Sublingual tablet effective in back pain management??
  Ans: Yes. It can be given for decreasing the back pain. However, you should consult your doctor for the exact cause of your back pain and then start the treatment. Do not self-medicate yourself with Ugesic Sublingual tablet as the cause of back pain can be different for different person.
• Q. Q. Is Ugesic Sublingual tablet affective in gout management??
  Ans: Yes. Ugesic Sublingual tablet can be given for the treatment of acute gout. Research studies have shown Ugesic Sublingual tablet to be highly effective in the treatment of acute gout.
• Q. Q. Can you donate blood when on the medication with Ugesic Sublingual tablet??
  Ans: Yes. You can donate blood when on Ugesic Sublingual tablet. Do inform your doctor before donating blood.
• Q. Q. Can I use Ugesic Sublingual tablet if I am a diabetic??
  Ans: Ugesic Sublingual tablet in a diabetic patient can only be taken only by consulting a doctor because these medicines have the propensity to cause renal failure when taken for a long period. Diabetes itself causes renal Ugesic Sublingual tablet so taking piroxicam can lead to increased risk of renal failure by many folds.
• Q. Q. Can I use Ugesic Sublingual tablet if I have a deranged renal function??
  Ans: No. Ugesic Sublingual tablet should not be taken if you have a abnormal renal function because long-term administration of NSAIDs has resulted in renal papillary necrosis and another renal injury.
• Q. Q. Can Ugesic Sublingual tablet lead to skin reactions??
  Ans: Yes. Ugesic Sublingual tablet is known to cause skin reactions which can be very severe such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. These serious events may occur without warning. You should inform your doctor if you feel you have a mild rash and immediately discontinue the drug.
• Q. Q. Can I use Ugesic Sublingual tablet if I am pregnant??
  Ans: No. Ugesic Sublingual tablet should not be taken in pregnancy. It causes premature closure of the ductus arteriosus which can lead to fetal heart failure and death of the baby.
• Q. Q. Can I use Ugesic Sublingual tablet if I have peptic ulcer disease??
  Ans: No. Ugesic Sublingual tablet is contraindicated in cases of active peptic ulcer disease. Ugesic Sublingual tablet is known to cause gastric ulceration and bleeding.
• Q. Q. Can I use Ugesic Sublingual tablet if I have asthma??
  Ans: Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory (NSAID) drugs like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
• Q. Q. Can Ugesic Sublingual tablet lead to difficulty in conception??
  Ans: Yes. Ugesic Sublingual tablet can sometimes cause reversible infertility. Piroxicam by its mechanism of action may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
• Q. Q. Can Ugesic Sublingual tablet be used with diuretics??
  Ans: No. Ugesic Sublingual tablet should not be used with diuretics. Ugesic Sublingual tablet reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
• Q. Q. Can Ugesic Sublingual tablet be used with lithium??
  Ans: No. Ugesic Sublingual tablet should not be used with lithium. Ugesic Sublingual tablet leads to an elevation of plasma lithium levels and a reduction in renal lithium clearance. This is because of inhibition of renal prostaglandin synthesis by the NSAID. Consult and inform your doctor before starting this medication.
• Q. Q. Can Ugesic Sublingual tablet be used with warfarin??
  Ans: No. Ugesic Sublingual tablet should be avoided with warfarin as they both lead to increase in bleeding tendencies. Inform your doctor if you are taking any of the medications. If given together then the therapy should be monitored closely.
• Q. Q. What increases the chances of getting a gastric ulcer when I am already taking Ugesic Sublingual tablet??
  Ans: The chances of gastric ulceration increases if you take medicines like corticosteroids and anticoagulants. Long term use, alcohol, smoking and old age are few other factors which can increase the chances of ulceration.
• Q. Q. Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Ugesic Sublingual tablet??
  Ans: Patients who had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAID medicine or for pain right before or after heart bypass surgery.
• Q. Q. What are the serious side effects of Ugesic Sublingual tablet??
  Ans: GI discomfort and, rarely, serious GI side effects, such as ulcers and bleeding, serious skin side effects such as exfoliative, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis, liver failure, renal damage.

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