Tibirim Inh 450 mg/300 mg Tablet is a combination medicine used in the treatment of tuberculosis. It prevents the growth of the microorganisms that cause the infection. Tibirim Inh 450 mg/300 mg Tablet is a prescription medicine and it is to be taken as suggested by the doctor. It should be taken in an empty stomach and take it at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The course of the treatment must be completed even if you feel better. Sudden discontinuation of the treatment may affect the potency of the medicine. The medicine may take some to show its effects on the symptoms. However, it is advised to consult the doctor if you feel an aggravation of the condition or if your condition does not improve. Some common side effects of this medicine are nausea, vomiting, fever, dark-colored urine, sweating, increased saliva, etc. To cope up with the side effects, you should drink plenty of water. If any of the side effects get aggravated, you must consult your doctor immediately. Generally, serious side effects are rare. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help. Before taking this medicine, you should tell your doctor if you are taking any medicines for any health condition. Patients with liver and kidney ailments must take this medicine with proper consultation and caution. Pregnant or breastfeeding women should also consult with the doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. During the treatment, you must take adequate rest and eat a healthy diet for a faster recovery. While on the medication, your doctor may ask for a few laboratory and diagnostic tests to know the effects of the medicine on your body.

• Rash
• Vomiting
• Jaundice
• Fever
• Increased liver enzymes
• Nausea
• Peripheral neuropathy (tingling and numbness of feet and hand)

If you miss a dose of Tibirim Inh 450 mg/300 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Q. Q. What is Tibirim Inh 450 mg/300 mg Tablet??
  Ans: Tibirim Inh 450 mg/300 mg Tablet is a combination of two medicines: Rifampicin and Isoniazid. It is used in the treatment of tuberculosis. Rifampicin works by inactivating a bacterial enzyme (RNA-polymerase) which is required by tuberculosis bacteria to make essential proteins and reproduce. Isoniazid prevents the tuberculosis causing bacteria from forming their own protective covering. Together, they kill the bacteria and eradicate the infection.
• Q. Q. What is the most important information I should know about the Tibirim Inh 450 mg/300 mg Tablet??
  Ans: Take the proper course of drug that has been prescribed to you. Do not stop in between even if you begin to feel better. Avoid alcohol while taking this medicine as it increases the risk of damage to your liver during treatment. Tell your doctor immediately if you experience vision changes, loss of appetite, tiredness, stomach pain, nausea or vomiting, yellow skin or eyes or dark-colored urine.
• Q. Q. What is the best time to take Tibirim Inh 450 mg/300 mg Tablet??
  Ans: Take Tibirim Inh 450 mg/300 mg Tablet exactly as directed by your doctor. It is best to take the medicine on an empty stomach one hour before or two hours after meals.
• Q. Q. Does Tibirim Inh 450 mg/300 mg Tablet cause change in urine color/turn urine orange??
  Ans: Yes, Tibirim Inh 450 mg/300 mg Tablet can change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful.
• Q. Q. Does the use of Tibirim Inh 450 mg/300 mg Tablet make birth control pills ineffective??
  Ans: Yes, Tibirim Inh 450 mg/300 mg Tablet can make birth control pills less effective. So, ask the doctor about using a birth control method which does not affect your hormone levels (such as a condom, diaphragm and spermicide).
• Q. Q. What are the instructions for storage and disposal of Tibirim Inh 450 mg/300 mg Tablet??
  Ans: Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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