Spirox-D 250mg/10mg Tablet is a combination of two medicines used in the prevention of migraines. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraines. Spirox-D 250mg/10mg Tablet may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop. Using of the medicine may cause few common side effects such as flu-like symptoms, indigestion, and dryness in the mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms. Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholics or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

• Indigestion
• Dryness in mouth

If you miss a dose of Spirox-D 250mg/10mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Q. Q. What is Spirox-D 250mg/10mg Tablet??
  Ans: Spirox-D 250mg/10mg Tablet is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.
• Q. Q. Can I stop taking Spirox-D 250mg/10mg Tablet when my migraine symptoms are relieved??
  Ans: No, do not stop taking Spirox-D 250mg/10mg Tablet until advised by your doctor.
• Q. Q. Can the use of Spirox-D 250mg/10mg Tablet cause diarrhea??
  Ans: Yes, the use of Spirox-D 250mg/10mg Tablet can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.
• Q. Q. Are there any specific contraindications associated with the use of Spirox-D 250mg/10mg Tablet??
  Ans: The use of Spirox-D 250mg/10mg Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.
• Q. Q. Can the use of Spirox-D 250mg/10mg Tablet cause damage to kidneys??
  Ans: Yes, the long-term use of Spirox-D 250mg/10mg Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.
• Q. Q. Can I take a higher than the recommended dose of Spirox-D 250mg/10mg Tablet??
  Ans: No, taking a higher than the recommended dose of Spirox-D 250mg/10mg Tablet can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.
• Q. Q. What are the recommended storage conditions for Spirox-D 250mg/10mg Tablet??
  Ans: Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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