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Spexib Capsule

Product Informations: Spexib Capsule

In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Spexib Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Take this medicine in the dose and duration as advised by your doctor. Spexib Capsule may be taken with or without food, but it is better to take it at a fixed time.
Spexib Capsule is used in the treatment of non-small cell lung cancer. It shows its working by stopping or slowing down the growth of cancer cells. Spexib Capsule should be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Fatigue, nausea, vomiting, and diarrhea are some common side effects of this medicine. Some serious side effects that might occur which need doctor consultation include tiredness, itchy skin, yellowing of your skin, and chest pain or discomfort, changes in your heartbeat. Your doctor may perform some blood tests before and after the treatment to check for liver, or blood sugar level. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
  • Fatigue
  • Nausea
  • Vomiting
Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Spexib Capsule. Please consult your doctor.

Pregnancy : CONSULT YOUR DOCTOR

Spexib Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life

threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding : CONSULT YOUR DOCTOR

Information regarding the use of Spexib Capsule during breastfeeding is not available. Please consult your doctor.

Driving : UNSAFE

Spexib Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney : SAFE IF PRESCRIBED

Spexib Capsule is safe to use in patients with kidney disease. No dose adjustment of Spexib Capsule is recommended.

Liver : SAFE IF PRESCRIBED

Spexib Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Spexib Capsule may not be needed in these patients. Please consult your doctor.

  • Q. Q. What is Spexib Capsule??
    Ans: Spexib Capsule is a cancer medicine that contains the active substance ceritinib. It is used to treat patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC).
  • Q. Q. What is ALK-positive NSCLC??
    Ans: Anaplastic lymphoma kinase (ALK) gene is present in all the cells. When it loses its original structure, it changes its normal behavior and multiplies abnormally, causing lung cancer. This type of lung cancer is called ALK-positive NSCLC.
  • Q. Q. How does Spexib Capsule treat ALK-positive NSCLC??
    Ans: Spexib Capsule treat ALK-positive NSCLC that has spread to other parts of the body. By blocking the activity of the abnormal ALK gene, it shrinks the tumor and also stops its further growth.
  • Q. Q. How should I take Spexib Capsule??
    Ans: Take this medicine on an empty stomach, do not eat for 2 hours before, and do not eat for 2 hours after taking Spexib Capsule. Talk to your doctor in case of any doubts.
  • Q. Q. How will you know that Spexib Capsule is working??
    Ans: Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.
  • Q. Q. Are there any serious side effects of Spexib Capsule??
    Ans: Yes, some people may develop serious side effects after taking this medicine. These may include fast or irregular heart rate, chest pain, lung inflammation (pneumonitis), liver disease, or severe diarrhea. Your doctor may need to adjust your treatment or stop Spexib Capsule temporarily or permanently.
  • Q. Q. What should I do if I develop liver problems while taking Spexib Capsule??
    Ans: If you develop liver problems while taking this medicine, you must look for some signs and symptoms. These may include excessive tiredness, yellowish discoloration of your skin or white portion of the eyes, dark or brown urine, nausea, vomiting, or decreased appetite. Additionally, you may develop itching, easy bruising, and also pain on the right side of your stomach. In case you observe any of these, you should consult your doctor without any delay.
  • Q. Q. Can Spexib Capsule affect my lungs? What should I do??
    Ans: Yes, this medicine might cause inflammation of the lungs (called pneumonitis). It is advisable to notify your doctor right away if you develop any new or worsening symptoms, including shortness of breath, trouble breathing, cough, or fever.
  • Q. Q. How to get relief from diarrhea while on treatment with Spexib Capsule??
    Ans: Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), orange, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soups and juice frequently to hydrate yourself.
  • Q. Q. Does Spexib Capsule cause vision problems??
    Ans: Yes, this medicine may cause vision problems. A regular eye examination is recommended in patients taking Spexib Capsule. If you notice any change in your vision or blurred vision, talk to your doctor.
  • Q. Q. I am a diabetic patient, will Spexib Capsule affect my sugar level??
    Ans: Spexib Capsule might cause a rise in your sugar level. Monitor your blood sugar level regularly and consult your doctor immediately if you notice excessive thirst and hunger, increased frequency of urination, headaches, trouble thinking or concentrating.
  • Q. Q. I have noticed some changes in my skin after taking Spexib Capsule. What should I do??
    Ans: Use a moisturizer to get relief from rashes, dry and itchy skin. Wear loose-fit cotton clothes and try to stay at an ambient room temperature. These conditions tend to resolve once treatment is stopped. However, if you develop yellow discoloration of your skin, inform your doctor immediately as this could be a sign of a liver problem.

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References

FDA approved prescribing information. Levocitrizine; 1995 [revised May 2007]. [Accessed 01 Apr. 2019] (online) Available from: Read More

European Medicne Agency. Revised assessment report: Ambroxol and bromhexine containing medicinal products. 2015. [Accessed 01 Apr. 2019] (online) Available from: Read More

ScienceDirect. Ambroxol. [Accessed 01 Apr. 2019] (online) Available from: Read More

Levocitrizine. Slough, Berkshire: UCB Pharma Limited; 2007 [revised 27 Mar. 2019]. [Accessed 01 Apr. 2019] (online) Available from: Read More


All Substitutes Product.


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Same salt composition: Ceritinib (150mg)

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