Sitacip M 50mg/500mg Tablet ER is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chances of having a heart attack or stroke. Sitacip M 50mg/500mg Tablet ER may be prescribed alone or along with other diabetes medications. It works best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels, and what other medicines you are taking. Taking it with meals helps to reduce the chances of developing an upset stomach. You should take it regularly, at the same time each day, to get the most benefit and you should not stop unless your doctor recommends it. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes. The most common side effects of taking Sitacip M 50mg/500mg Tablet ER include diarrhea, nausea, vomiting, upset stomach, headache, and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin or sulfonylurea, so you need to know how to recognize and deal with it. This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver, or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines may affect Sitacip M 50mg/500mg Tablet ER so tell your doctor about all the other medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood glucose. Your doctor will check your kidney function and blood sugar levels before and during treatment.

• Nausea
• Vomiting
• Diarrhea
• Decreased appetite
• Abdominal bloating
• Upper respiratory tract infection

If you miss a dose of Sitacip M 50mg/500mg Tablet ER, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Q. Q. What is Sitacip M 50mg/500mg Tablet ER??
  Ans: Sitacip M 50mg/500mg Tablet ER is a combination of two medicines: Sitagliptin and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus. It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Sitagliptin inhibits the enzyme DPP4 and increases the release of insulin from the pancreas. This combination is not indicated for the patients below 18 years of age.
• Q. Q. Can the use of Sitacip M 50mg/500mg Tablet ER lead to Vitamin B12 deficiency??
  Ans: Yes, the use of Sitacip M 50mg/500mg Tablet ER can cause Vitamin B12 deficiency on long-term use. It interferes with the absorption of Vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems as a result of which the patient can feel tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.
• Q. Q. What are the possible side effects of Sitacip M 50mg/500mg Tablet ER??
  Ans: The use of Sitacip M 50mg/500mg Tablet ER is associated with common side effects like hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effect like lactic acidosis. On long-term use it can also lead to Vitamin B12 deficiency.
• Q. Q. Are there any specific conditions in which Sitacip M 50mg/500mg Tablet ER should not to be taken??
  Ans: The use of Sitacip M 50mg/500mg Tablet ER should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine should be avoided in patients with severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis or diabetic ketoacidosis.
• Q. Q. Is it safe to take alcohol while I am taking Sitacip M 50mg/500mg Tablet ER??
  Ans: No, it is not safe to alcohol along with Sitacip M 50mg/500mg Tablet ER, as it can increase the chances of lactic acidosis.
• Q. Q. What are the instructions for storage and disposal of Sitacip M 50mg/500mg Tablet ER??
  Ans: Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
• Q. Q. Can the use of Sitacip M 50mg/500mg Tablet ER lead to lactic acidosis??
  Ans: Yes, the use of Sitacip M 50mg/500mg Tablet ER can lead to lactic acidosis. It is a medical emergency which is caused by the increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin and therefore, it is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Sitagliptin + Metformin and immediately consult your doctor.

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