Serom 450mg Tablet is an antibiotic, used in the treatment of all forms of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. It may be used alone or in combination with other medicines to fight serious infections. Serom 450mg Tablet may also be given to people who are carriers (people who are infected, yet do not show any signs and symptoms of infection). It should be taken on an empty stomach, at least 30 minutes before a meal or 2 hours after a meal. It should be taken in the dose and duration as advised by the doctor. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat. Some people may develop side effects like low blood platelets, headache, dizziness, vomiting, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or will not go away. Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver, kidney or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests for liver function tests while using this medicine.

• Vomiting
• Nausea
• Abdominal pain
• Skin rash
• Hepatitis (viral infection of liver)

If you miss a dose of Serom 450mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Q. Q. Is rifampin a penicillin/amoxicillin/sulfa drug??
  Ans: No. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has a structure and mechanism of action different from penicillin or amoxicillin (amoxicillin belongs to the class of penicillin antibiotics). The chemical structure and mechanism of action of rifampin is different from sulfa drugs
• Q. Q. Is rifampin bacteriostatic or bactericidal??
  Ans: Rifampin is a bactericidal drug. It acts by blocking the activity of a bacterial enzyme called DNA-dependent RNA polymerase which essential for important life processes in the bacteria, thereby killing the bacteria
• Q. Q. Is rifampin an inducer or inhibitor??
  Ans: Rifampin is an inducer (increases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
• Q. Q. What is R-cin 600 used for??
  Ans: R-cin 600 is a trade name for active drug rifampin 600 mg. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It is also used in the prevention of meningococcal meningitis and Haemophilus influenza infections. It may also be used in combination with other drugs to treat infections-Brucellosis, Legionnaires disease or serious staphylococcal infections
• Q. Q. What is R-cinex/Macox plus/R-cinex 600??
  Ans: R-cinex and Macox plus are trade names for a combination of active drugs rifampin and isoniazid. It is used in the treatment of tuberculosis. R-cinex 600 and Macox plus contains 600 mg of active drug rifampin and 300 mg of active drug isoniazid
• Q. Q. Can I take rifampin with ibuprofen/acetaminophen (Tylenol)??
  Ans: Rifampin has no known serious drug interaction with ibuprofen or acetaminophen (trade name: Tylenol). Inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
• Q. Q. Does rifampin cause weight gain/weight loss/ hair loss/ constipation/ yeast infection??
  Ans: No. Changes in body weight, hair loss or triggering constipation are not among the known side effects of rifampin. Rifampin is an antibiotic commonly used in the treatment of tuberculosis and leprosy. It has no known effect on causing yeast infections
• Q. Q. Does rifampin cause headaches??
  Ans: Yes. Headache is a possible side effect of rifampin
• Q. Q. Does rifampin change urine color/turn urine orange??
  Ans: Yes. Taking rifampin may change the color of your urine (skin, sweat, saliva, tears and feces) to brownish-red or orange. This effect is not harmful
• Q. Q. Does rifampin cause liver damage??
  Ans: Rifampin is safe when used at prescribed doses for the prescribed duration. Constant monitoring of liver function is important while on treatment with rifampin. Taking drugs like saquinavir, ritonavir with rifampin can cause severe liver damage. Do consult your doctor if you have any liver problem before taking rifampin.

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