Macrozide 1000 Tablet is an antibiotic that belongs to a class of medicines known as anti tuberculosis drugs. It is used in the treatment of tuberculosis, an infectious disease that mainly affects the lungs and in some cases other parts of the body. Macrozide 1000 Tablet is given in combination with at least one other tuberculosis medicine. It acts by killing the causative bacteria. It should be used in the dose and duration as advised by your doctor. This medicine may be taken with or without food, preferably at a fixed time every day to avoid a missed dose. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Please let your doctor know about any changes in your weight as the dose of this medicine depends on the overall body weight of a person. Any changes in weight might need dose modification. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose, as it may increase the side effects. Inform your doctor if you notice signs of jaundice i.e. yellowing of eyes or skin, dark urine, stomach pain or joint pain. You may also develop hepatitis (viral infection of the liver), increased liver enzymes and joint pain as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and might need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

• Hepatitis (viral infection of liver)
• Increased liver enzymes
• Joint pain

If you miss a dose of Macrozide 1000 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class::Nicotinic acid derivatives|Habit Forming::No|Therapeutic Class::ANTI INFECTIVES|Action Class::Mycobacterial fatty acid synthase

• Q. Q. What is Macrozide 1000 Tablet and what is it used for??
  Ans: Macrozide 1000 Tablet is an antibiotic. It is used in combination with other antibiotics in the treatment of tuberculosis
• Q. Q. Is Macrozide 1000 Tablet bactericidal??
  Ans: Macrozide 1000 Tablet is both a bacteriostatic and a bactericidal antibiotic. It stops the growth of bacteria (bacteriostatic) in certain cases and kills (bactericidal) the tuberculosis causing bacteria in other cases
• Q. Q. How does Macrozide 1000 Tablet work/treat tuberculosis??
  Ans: Macrozide 1000 Tablet kills or stops growth of bacteria that causes tuberculosis (Mycobacterium tuberculosis). The exact mechanism of action for Macrozide 1000 Tablet is not known
• Q. Q. How does Macrozide 1000 Tablet cause hyperuricemia and gout??
  Ans: Following oral intake of Macrozide 1000 Tablet, it gets converted in the body to pyrazinoic acid (active chemical form of Macrozide 1000 Tablet). Pyrazinoic acid blocks the excretion of urates (salt form of uric acid) by the kidneys. This causes an increase in blood levels of uric acid (hyperuricemia). Excess uric acid accumulation between joints causes pain, swelling, redness and stiffness in joints (gout).
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  Ans:

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