Itarex 400mg Tablet SR belongs to a group of medicines called antifungals. It works by stopping the growth of fungi and is used to treat infections of the mouth, throat, vagina, and other parts of the body including fingernails and toenails. It kills fungi by destroying the fungal cell membrane. Itarex 400mg Tablet SR should be taken in the dose and duration as prescribed by your doctor. It should be swallowed whole and can be taken with food. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop the treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment. Tell your doctor if the infection does not get better or if it gets worse. The most common side effects of this medicine include nausea, common cold, cough, blurred vision, and a problem with menstrual periods. You could ask your doctor about ways of preventing or reducing these effects. Get emergency medical help if you have signs of an allergic reaction like severe skin rash, tingling, difficulty breathing, swelling of your face, lips, tongue, or throat. Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking this medicine if you have ever had heart failure, a weak immune system (including HIV/AIDS), kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver by testing your blood.

• Common cold
• Cough
• Blurred vision
• Menstrual disorder

If you miss a dose of Itarex 400mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class::Azoles {Triazoles}|Habit Forming::No|Therapeutic Class::OPHTHAL|Action Class::Fungal ergosterol synthesis inhibitor

• Q. Q. What is Itarex 400mg Tablet SR used for??
  Ans: Itarex 400mg Tablet SR is used to treat fungal infections caused by Trichophyton spp., Microsporum spp., and Epidermophyton floccosum. The infections caused could be ringworm infection, infection of the feet, or infection in the groin and buttocks. This medicine also treats persistent infection of fingernails and toenails, persistent candida (yeast) infections of vagina or candida (yeast) infections of the mouth or throat in patients with lower disease resistance. It is also used in the treatment of cryptococcal infection and infections caused by Histoplasma, aspergillus, and Blastomyces.
• Q. Q. For how long do I need to take Itarex 400mg Tablet SR??
  Ans: The dose and length of treatment depends on the type and site of infection and your response to the treatment. For example, if you are taking Itarex 400mg Tablet SR for athlete’s foot (fungal infection of the skin on the feet and between the toes), the dose may need to be taken for 30 days, on the other hand, if you are taking it for candidal infection of the vagina, the dose may span from 1 day to 3 days depending on the dosage advised by the doctor.
• Q. Q. What should I do if I skip a dose of Itarex 400mg Tablet SR??
  Ans: Take the missed dose as soon as you remember. However, if it is time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the forgotten dose.
• Q. Q. I am taking Itarex 400mg Tablet SR for nail infection but there does not seem to be any improvement. Can I stop taking it??
  Ans: No, you should not stop taking Itarex 400mg Tablet SR without completing the entire course because doing so may not completely cure the fungal infection. It usually takes about 6-9 months for nail lesions to disappear because after the medicine eliminates the fungus, the new nail takes several months to grow. Do not worry if you do not see any improvement during the treatment.
• Q. Q. Why has my doctor asked me to get blood tests done??
  Ans: Your doctor is probably trying to monitor your liver’s functioning. Itarex 400mg Tablet SR may cause serious liver damage. Therefore, if you develop loss of appetite, nausea, vomiting, dark urine, or abdominal pain while taking Itarex 400mg Tablet SR, you should tell your doctor immediately.
• Q. Q. Can I take antacid and Itarex 400mg Tablet SR together??
  Ans: Itarex 400mg Tablet SR can be utilized by the body if there is sufficient acid in the stomach. Medicines for stomach ulcers, heartburn, or indigestion neutralize the acid produced by the stomach. Therefore, take antacids or any such medicine about 2 hours after taking Itarex 400mg Tablet SR. If you are taking antacids (medicines that stop the production of stomach acid), take Itarex 400mg Tablet SR capsules with a drink of cola.
• Q. Q. What is drug resistance? Is it possible to develop resistance to Itarex 400mg Tablet SR??
  Ans: Sometimes it happens that the fungi get modified in your body and the medicine no longer works. This is called drug resistance. Resistance to Itarex 400mg Tablet SR has been reported with some candida species (krusei, glabrata, and tropicalis). Itarex 400mg Tablet SR should not be used for infection caused due to these species. Take the complete course of Itarex 400mg Tablet SR to avoid drug resistance.
• Q. Q. I have been on alprazolam for quite some time. Is it okay if I start Itarex 400mg Tablet SR now??
  Ans: Yes, you can take both Alprazolam and Itarex 400mg Tablet SR together, but keep a watch on the side effects of alprazolam such as lightheadedness or drowsiness. If side effects appear after taking Itarex 400mg Tablet SR, talk to your doctor who will modify the dose of alprazolam.
• Q. Q. My doctor prescribed Itarex 400mg Tablet SR to me but not to my friend who had a similar fungal infection because she was on dofetilide. Why is it so??
  Ans: Your doctor did not prescribe Itarex 400mg Tablet SR to your friend because Itarex 400mg Tablet SR interferes with the working of dofetilide. This interference can cause disturbed electrical activity of the heart, which can be harmful to the patient.

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