Isonex 300mg Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis. Isonex 300mg Tablet should be used in the dose and duration as advised by your doctor. It is to be taken on an empty stomach. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early can result in treatment failure and increase the side effects too. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned. Some common side effects of this medicine include tingling and numbness of feet and hand (peripheral neuropathy). Inform your doctor if you notice signs of jaundice, i.e., yellowing of eyes or skin, dark urine, stomach pain, or joint pain. You may also develop hepatitis (viral infection of the liver) or increased liver enzymes as side effects of this medicine. Please consult your doctor, as these side effects require medical attention and need dose modification. Your doctor may monitor your liver function while on treatment with this medicine. Avoid drinking alcohol as this may have additional adverse effects on the liver. Pregnant or breastfeeding women should consult their doctor before using this medicine.

• Hepatitis (viral infection of liver)
• Skin rash
• Itching
• Dizziness
• Lethargy

If you miss a dose of Isonex 300mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class::Nicotinic acid derivatives|Habit Forming::No|Therapeutic Class::ANTI INFECTIVES|Action Class::Mycolic acid inhibitors- INH

• Q. Q. Is Isonex 300mg Tablet an antibiotic??
  Ans: Isonex 300mg Tablet is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
• Q. Q. Is Isonex 300mg Tablet chemotherapy/chemotherapy drug??
  Ans: Isonex 300mg Tablet is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
• Q. Q. Is Isonex 300mg Tablet bacteriostatic or bactericidal??
  Ans: Isonex 300mg Tablet is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
• Q. Q. Is Isonex 300mg Tablet safe??
  Ans: Yes. Isonex 300mg Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor
• Q. Q. Is Isonex 300mg Tablet a MAOI??
  Ans: Isonex 300mg Tablet has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
• Q. Q. Is Isonex 300mg Tablet a sulfa drug??
  Ans: No. The chemical structure and mechanism of action of Isonex 300mg Tablet is different from sulfa drugs
• Q. Q. Is Isonex 300mg Tablet an inducer or inhibitor??
  Ans: Isonex 300mg Tablet is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
• Q. Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin??
  Ans: There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
• Q. Q. Does Isonex 300mg Tablet cause weight loss/weight gain/hair loss/diarrhea/affect menstruation??
  Ans: Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isonex 300mg Tablet. You may experience few of these side effects while on multi drug (including Isonex 300mg Tablet) treatment for tuberculosis
• Q. Q. Does Isonex 300mg Tablet cause acne/make you tired/cause constipation??
  Ans: You may experience unusual tiredness, constipation or acne while on treatment with Isonex 300mg Tablet. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
• Q. Q. Does Isonex 300mg Tablet affect birth control??
  Ans: Isonex 300mg Tablet has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

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