Eribilin Injection is used in the treatment of breast cancer. It is used to treat adults with breast cancer that has spread to other parts of the body, and who have already received other anticancer medicines after the cancer has spread. Eribilin Injection can be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy. It is given as injection under the supervision of doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include weakness, hair loss, nausea, and constipation. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid and electrolytes levels. You might experience numbness, tingling or pricking sensations in your hands and feet. Consult with your doctor immediately if it bothers you or would not go away on their own. Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

• Weakness
• Hair loss
• Nausea
• Constipation
• Decreased white blood cell count
• Fatigue
• Peripheral neuropathy (tingling and numbness of feet and hand)

Chemical Class::Synthetic analogue of halichondrin B|Habit Forming::No|Therapeutic Class::ANTI NEOPLASTICS|Action Class::Antimicrotubule agents- Non Taxanes

• Q. Q. Is hair loss caused by Eribilin Injection irreversible??
  Ans: Hair loss is a common side effect of Eribilin Injection. It could be reversible but the severity of hair loss varies from person to person. Consult your doctor if you have any concerns regarding hair loss.
• Q. Q. How long can I stay on Eribilin Injection??
  Ans: Eribilin Injection is usually given on Days 1 and 8 of each recommended 21-day cycle. The duration of treatment varies from person to person. The number of cycles required for effective treatment will be decided by your doctor. Depending on the results of your blood tests, the doctor may need to delay administration of the medicine until the blood tests return to normal. If required, the doctor may also decide to reduce the dose you are given.
• Q. Q. How is Eribilin Injection Mesylate administered??
  Ans: Eribilin Injection will be given to you by a doctor or healthcare professional as an injection into a vein, over a period of 2 to 5 minutes. The dose required will be decided based on your body surface area (expressed in square metres, or m2) which is calculated from your weight and height. The doctor may adjust the usual dose based on your blood test results or other factors. To ensure that the whole dose of Eribilin Injection is given, it is recommended that a saline solution is flushed into the vein after Eribilin Injection is given.
• Q. Q. What are the serious side effects of Eribilin Injection??
  Ans: Eribilin Injection can cause serious side effects which include low white blood cell count (neutropenia). This can lead to serious infections that could lead to death. It can also cause numbness, tingling, or pain in your hands or feet (peripheral neuropathy). Peripheral neuropathy is common with Eribilin Injection and sometimes can be severe. It can cause harm to the baby when administered to a pregnant woman.
• Q. Q. When can I plan a pregnancy if I am using Eribilin Injection??
  Ans: Women of childbearing age should use effective contraception during and up to 3 months after treatment with Eribilin Injection.It may cause serious birth defects and should not be used if you are pregnant unless it is thought clearly necessary after carefully considering all the risk to you and the baby.
• Q. Q. What precautions should be followed while handling Eribilin Injection??
  Ans: Eribilin Injection should be handled carefully. Avoid any contact with skin, eyes, mouth and insides of nose. It is recommended to use gloves, goggles, and protective clothing while handling the medicine. If the skin comes into contact with the solution, it should be washed immediately and thoroughly with soap and water. Similarly, if your eyes, mouth or nose come in contact with Eribilin Injection, flush the area thoroughly with water. Pregnant staff should not handle Eribilin Injection.
• Q. Q. In which solution should Eribilin Injection injection be diluted??
  Ans: Eribilin Injection may be diluted in up to 100 ml of sodium chloride 9 mg/ml (0.9%) solution and not in 5% dextrose. It should be given under the supervision of a physician experienced in giving cancer chemotherapy and should be administered by a health care professional only.

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