Entacom Tablet is used in the treatment of Parkinson's disease. It helps to treat wearing-off symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Entacom Tablet is usually used in combination with carbidopa/levodopa. It may be taken with or without food, preferably at bedtime. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. This medication mustn't be stopped suddenly without talking to the doctor as it may worsen your condition. Your doctor may advise for periodic skin examination as it can cause melanoma. Some common side effects of this medicine include nausea, vomiting, fatigue, confusion, constipation, insomnia(difficulty sleeping), nightmares, and increased sweating. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is common to have diarrhea with this medicine, so drink plenty of fluids and watch for weight loss. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, and hallucinations. It may cause your urine to change in a brownish-orange color but it is not harmful and usually resolves once treatment is completed. Please consult your doctor if these side effects worry you or do not go away.

• Vomiting
• Fatigue
• Confusion
• Constipation
• Insomnia (difficulty in sleeping)
• Nightmares
• Hallucination
• Increased sweating
• Fall
• Urine discoloration
• Dizziness
• Diarrhea
• Muscle coordination impaired
• Ischemic heart disease
• Heart attack
• Abdominal pain
• Dryness in mouth

If you miss a dose of Entacom Tablet, skip it and continue with your normal schedule. Do not double the dose.

• Q. Q. Can Entacom Tablet be crushed or split? If not, then how it should be taken??
  Ans: No, Entacom Tablet should not be crushed or split. Take it as a whole with a full glass of water at the same time as you take a dose of levodopa
• Q. Q. Does Entacom Tablet have any effect on urine color??
  Ans: Yes, Entacom Tablet may cause your urine to change to a brownish-orange color. This effect is common and is not harmful.
• Q. Q. Will Entacom Tablet make me sleepy??
  Ans: The combined use of Entacom Tablet and levodopa has been associated with cases of excessive daytime sleepiness and sudden sleep onset episodes. If you experience these symptoms, then you should neither drive nor operate other complex machinery. Consult your doctor if it becomes troublesome.
• Q. Q. What is meant by impulse control disorder caused by Entacom Tablet??
  Ans: In impulse control disorders, you may get urges or cravings to behave in ways that are unusual for you. In such disorders, you cannot resist the impulse, drive or temptation to carry out certain activities that could harm yourself or others. Additionally, it may include addictive gambling, excessive eating or spending, an abnormally high sex drive or a preoccupation with an increase in sexual thoughts or feelings. In such a case, your doctor may suggest dose reduction or discontinuation of dose.
• Q. Q. What if I accidentally take more than the recommended doses of Entacom Tablet??
  Ans: In case you take more than the recommended doses of Entacom Tablet, you may experience confusion, decreased activity, sleepiness, decreased muscle tone, skin discoloration, and urticaria. If any such symptoms occur, you should seek immediate medical attention in a nearby hospital or contact your doctor.
• Q. Q. Does Entacom Tablet cross the blood-brain barrier??
  Ans: No, Entacom Tablet does not cross the blood-brain barrier. It is useful in prolonging the duration of the benefit obtained from individual doses of levodopa.
• Q. Q. Does Entacom Tablet affect fertility??
  Ans: No, Entacom Tablet does not affect fertility. However, it should be avoided by pregnant and lactating women because there is no sufficient data to support the safety of this patient group.
• Q. Q. Is Entacom Tablet a dopamine agonist??
  Ans: No, it is not a dopamine agonist. Entacom Tablet is a selective and reversible inhibitor of COMT (catechol-O-methyltransferase) which works by increasing and maintaining sustained levels of levodopa when levodopa is given along with it.

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