E 2 Gel is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching); estrogen deficiency; and thinning of bones (osteoporosis). In some cases, E 2 Gel is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine. The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc. Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

• Breast enlargement
• Hair loss
• Uterine bleeding
• Depression
• Joint pain
• Leg cramps
• Leukorrhea
• Urinary tract infection
• Itching
• Irritable bladder

• Q. Q. What is E 2 Gel and what is it used for??
  Ans: E 2 Gel is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women, who are at high risk of fractures and have limited treatment choice.
• Q. Q. When and how to take E 2 Gel??
  Ans: Take E 2 Gel as per your doctor's advice. However, you must try to take E 2 Gel at the same time of each day, to ensure the consistent levels of medicine in your body.
• Q. Q. What if I miss a dose of E 2 Gel??
  Ans: If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.
• Q. Q. What are the most common side effects which I may experience while taking E 2 Gel??
  Ans: The common side effects associated with E 2 Gel are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if these persist, check with your doctor as soon as possible.
• Q. Q. What can I take for estrogen deficiency??
  Ans: For estrogen deficiency, treatment is based on the underlying cause. Your doctor may choose from a variety of medications depending upon whether your are young or old or have had your menopause. The medications will also depend upon whether you are estrogen deficient or have high progesterone levels, etc. You may be given bio-identical estradiol or estriol or counterbalance with natural progesterone.
• Q. Q. Who should not take E 2 Gel??
  Ans: E 2 Gel should not be taken by patients who have unusual vaginal bleeding, liver problems, or bleeding disorder. It should also be avoided to patients who are pregnant or are allergic to E 2 Gel. Patients who have had uterus or breast cancer, had a stroke or heart attack, or currently have or had blood clots should also avoid this medicine.
• Q. Q. What are the serious side effects of E 2 Gel??
  Ans: Serious side effects of E 2 Gel are uncommon and do not affect everyone. These serious side effects may include breast cancer, ovarian cancer, uterus cancer, stroke, heart attack, blood clots, gallbladder disease and dementia.

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