Celkeran 5mg Tablet is used in the treatment of some cancers of blood and lymphatic system. It may be also used to treat other kinds of cancer, as determined by the doctor. It is used alone or in combination with other cancer medicines. Celkeran 5mg Tablet should be taken empty stomach, or 1 hour before and 2 hours after a meal. But, try to have it at the same time every day for most benefits. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include anemia (low number of red blood cells), decreased blood cells (red cells, white cells, and platelets) decreased white blood cell count, infection, nausea and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Inform your doctor if you have a medical history, of bleeding disorders, heart or liver disease, radiation treatment or any infection. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with kidney, liver and heart function during treatment with this medicine. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

• Decreased blood cells (red cells, white cells, and platelets)
• Decreased white blood cell count (neutrophils)
• Decreased white blood cell count
• Bone marrow suppression
• Nausea
• Vomiting
• Diarrhea
• Mouth ulcer

If you miss a dose of Celkeran 5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Chemical Class::Nitrogen Mustard Compounds|Habit Forming::No|Therapeutic Class::ANTI NEOPLASTICS|Action Class::Alkylating agent

• Q. Q. How is Celkeran 5mg Tablet administered??
  Ans: Celkeran 5mg Tablet is administered orally in tablet form.
• Q. Q. Why is Celkeran 5mg Tablet toxic to cancer cells/ how does Celkeran 5mg Tablet work??
  Ans: Celkeran 5mg Tablet belongs to a class of drugs called nitrogen mustard derivatives which kill the cancer cells by interfering with DNA replication, and also by directly slowing or stopping their growth.
• Q. Q. Does Celkeran 5mg Tablet cause hair loss/constipation??
  Ans: No, hair loss or constipation has not been reported with the use of Celkeran 5mg Tablet.
• Q. Q. What is Celkeran 5mg Tablet used for??
  Ans: Celkeran 5mg Tablet is used to treat some types of blood cancers like Hodgkin's disease (cancer that starts in blood cells that are part of immune system), certain forms of non-Hodgkin's lymphoma, chronic lymphocytic leukemia (disease where the bone marrow produces a large number of abnormal white cells. It is also used to treat Waldenstrom's macroglobulinaemia (rare blood condition involving the release of an abnormal protein, macroglobulin, into the blood).
• Q. Q. How is Celkeran 5mg Tablet excreted??
  Ans: Celkeran 5mg Tablet is metabolized in liver to form nontoxic compounds which are excreted in urine.
• Q. Q. Does Celkeran 5mg Tablet need to be refrigerated??
  Ans: Celkeran 5mg Tablet has to be stored in a refrigerator at a temperature between 2 °C – 8 °C.

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