CIRCALTIN 25 MG TABLET helps treat depression. It reduces and gradually eliminates the symptoms of depression such as deep sadness, feelings of worthlessness, loss of interest in activities, sleep disturbances, tiredness, feelings of anxiety, and weight changes. CIRCALTIN 25 MG TABLET may be taken with or without food preferably at bedtime. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. If you have missed any doses, take it as soon as you remember and finish the full course of treatment even if you feel better. Do not stop taking it suddenly without talking to your doctor as it may worsen your symptoms. Some common side effects of this medicine include headache, nausea, fatigue, anxiety, insomnia (difficulty sleeping), and back pain. Other side effects that may also be observed are stomach pain, changes in body weight, diarrhea, and increased liver enzymes. However, these are temporary and usually resolve on their own in some time. Please consult your doctor if these do not subside or worry you. It even causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Before taking this medicine, please tell your doctor if you suffer from any liver problems or diabetes. If you have been taking this medicine for a long time, regular monitoring of blood and liver functions may be required. Be vigilant about unusual darkening or any changes in the color of your urine, light-colored stools, yellowing of skin or eyes, pain in the upper right part of your stomach, and unusual fatigue as this could be signs of liver problems. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine.

• Nausea
• Dizziness
• Fatigue
• Anxiety
• Insomnia (difficulty in sleeping)
• Back pain
• Abdominal pain
• Change in body weight
• Diarrhea
• Constipation
• Sleepiness
• Increased liver enzymes

If you miss a dose of CIRCALTIN 25 MG TABLET, skip it and continue with your normal schedule. Do not double the dose.

• Q. Q. What should I inform my doctor before starting treatment with CIRCALTIN 25 MG TABLET??
  Ans: Before taking this medicine inform your doctor if you are allergic to agomelatine or any of the other ingredients of this medicine, if your liver does not work properly (hepatic impairment) or if you are taking any other antidepressants or antibiotics.
• Q. Q. Can CIRCALTIN 25 MG TABLET damage my liver??
  Ans: Yes, this medicine can cause further serious or even life-threatening damage to the liver if you have ever had any liver problems. Inform your doctor immediately if you notice severe stomach pain (upper right side), dark urine, clay-colored stools, tiredness, itching, or jaundice (yellowing of the skin or eyes).
• Q. Q. I was taking an anti-depressant but my doctor has asked me to start taking CIRCALTIN 25 MG TABLET? Are there any side effects due to changes in medicines??
  Ans: If your doctor changes your previous antidepressant medicine to CIRCALTIN 25 MG TABLET, he/she will advise you on how you should discontinue your previous medicine when starting CIRCALTIN 25 MG TABLET. You may experience discontinuation symptoms like dizziness, numbness, sleep disturbances, agitation or anxiety, headaches, feeling sick, being sick, and shaking. These effects are usually mild to moderate and disappear spontaneously within a few days. Inform your doctor immediately if the symptoms worsen.
• Q. Q. How to store CIRCALTIN 25 MG TABLET??
  Ans: Store in the original package in order to protect from moisture. This medicine does not require any special temperature storage conditions. Keep this medicine out of the sight and reach of children.
• Q. Q. Can CIRCALTIN 25 MG TABLET be given to children??
  Ans: This medicine is not recommended in the treatment of depression in patients under 18 years of age since its safety and efficacy have not been established in this age group.

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