Amitril Plus 12.5 mg/5 mg Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety. Amitril Plus 12.5 mg/5 mg Tablet is taken with or without food. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for a long time may require regular monitoring of blood and liver functions. Some common side effects of this medicine include constipation, difficulty in urination, weight gain, confusion, orthostatic hypotension (sudden lowering of blood pressure on standing). This medicine may cause weight loss. In case of losing weight, consult a dietitian for dietary supplements or try to increase your food portion. Most of the common side effects tend to be mild. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects are rare. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts. Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Difficulty in urination
• Weight gain
• Confusion
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Tiredness
• Blurred vision
• Dryness in mouth
• Increased heart rate
• Uncoordinated body movements
• Depression
• Memory impairment

If you miss a dose of Amitril Plus 12.5 mg/5 mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

• Q. Q. Are there any important warnings associated with use of Amitril Plus 12.5 mg/5 mg Tablet??
  Ans: During the first few months of treatment, Amitril Plus 12.5 mg/5 mg Tablet may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.
• Q. Q. Can I stop taking Amitril Plus 12.5 mg/5 mg Tablet when my symptoms are relieved??
  Ans: No, you should continue to take Amitril Plus 12.5 mg/5 mg Tablet, even if you feel well. If you stop Amitril Plus 12.5 mg/5 mg Tablet suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
• Q. Q. How to manage weight gain associated with the use of Amitril Plus 12.5 mg/5 mg Tablet??
  Ans: There are reports which suggest that the use of Amitril Plus 12.5 mg/5 mg Tablet can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.
• Q. Q. What are the instructions for storage and disposal of Amitril Plus 12.5 mg/5 mg Tablet??
  Ans: Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
• Q. Q. Can the use of Amitril Plus 12.5 mg/5 mg Tablet cause sleepiness??
  Ans: Yes, Amitril Plus 12.5 mg/5 mg Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.
• Q. Q. Can the use of Amitril Plus 12.5 mg/5 mg Tablet affect my sexual life??
  Ans: The use of Amitril Plus 12.5 mg/5 mg Tablet can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.
• Q. Q. Can I drink alcohol while taking Amitril Plus 12.5 mg/5 mg Tablet??
  Ans: No, do not drink alcohol while you are taking Amitril Plus 12.5 mg/5 mg Tablet. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Amitril Plus 12.5 mg/5 mg Tablet.
• Q. Q. Can the use of Amitril Plus 12.5 mg/5 mg Tablet change the color of urine??
  Ans: Yes, Amitril Plus 12.5 mg/5 mg Tablet can the change the color of the urine to blue or green. This change of color is expected while using Amitril Plus 12.5 mg/5 mg Tablet, and it is not harmful. Your urine color becomes normal once you stop taking Amitril Plus 12.5 mg/5 mg Tablet.
• Q. Q. How long does Amitril Plus 12.5 mg/5 mg Tablet take to work??
  Ans: Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Amitril Plus 12.5 mg/5 mg Tablet, although some people will start to feel better sooner. When taking Amitril Plus 12.5 mg/5 mg Tablet, it is important to give it time to work.

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