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Affytericin-B Injection

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Product Informations: Affytericin-B Injection

In Severe fungal infections Affytericin-B Injection works by killing the fungi which can cause serious infections. It is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the fungi and yeast causing the infection are killed and do not become resistant. In Kala-azar Kala azar is a disease caused by leishmania parasites mainly by the bite of infected sandflies. Affytericin-B Injection helps to kill the infection causing parasites and helps to treat the infection. This medicine is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the parasites are killed and do not become resistant.

Your doctor or nurse will give you this medicine. Kindly do not self administer.
Affytericin-B Injection is an antifungal medication. It is used in the treatment of severe fungal infections and kala-azar. It kills the infection causing fungi and thus, treats the infection. Affytericin-B Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Before you take this medicine, inform your doctor if you suffer from diabetes, liver/kidney problems or are on dialysis or have low potassium level in blood. It may lead to a few common side effects like headache, vomiting, nausea, stomach cramps and fever. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Vomiting
  • Nausea
  • Stomach cramp
  • Fever
  • Anemia (low number of red blood cells)
  • Heartburn
  • Hyperventilation (rapid breathing)
  • Injection site reactions (pain, swelling, redness)
Alcohol : CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Affytericin

B Injection. Please consult your doctor.

Pregnancy : SAFE IF PRESCRIBED

Affytericin

B Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding : CONSULT YOUR DOCTOR

Affytericin

B Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving : UNSAFE

Affytericin

B Injection may cause side effects which could affect your ability to drive.

Kidney : SAFE IF PRESCRIBED

Affytericin

B Injection is safe to use in patients with kidney disease. No dose adjustment of Affytericin

B Injection is recommended. However, inform your doctor if you have any underlying kidney disease.

Liver : CONSULT YOUR DOCTOR

There is limited information available on the use of Affytericin

B Injection in patients with liver disease. Please consult your doctor.

If you miss a dose of Affytericin-B Injection, please consult your doctor.

  • Q. Q. Is Affytericin-B Injection fungistatic or fungicidal??
    Ans: Affytericin-B Injection is fungicidal in nature, it acts by killing the fungus
  • Q. Q. Is Affytericin-B Injection light sensitive??
    Ans: Affytericin-B Injection is not light sensitive
  • Q. Q. What is Affytericin-B Injection liposomal??
    Ans: Liposomal Affytericin-B Injection is a lipid-associated formulation. Liposomal encapsulation or incorporation into a lipid complex of Affytericin-B Injection can substantially improves drug safety especially nephrotoxicity associated with the drug
  • Q. Q. Is Affytericin-B Injection an antibiotic??
    Ans: Yes, Affytericin-B Injection is an antifungal antibiotic for the treatment of serious infections caused by fungi like fungal infections of one or more deep organs of the body, suspected fungal infections in patients with a raised temperature and neutropenia (reduced number of white blood cells [neutrophils]) and Visceral leishmaniasis (disease caused by a parasite)
  • Q. Q. Is Affytericin-B Injection testing dose needed??
    Ans: Yes, administration of Affytericin-B Injection is associated with allergy (severe and serious allergic) reaction, therefore it is recommended to administer a test dose before starting the therapy to check for sensitivity
  • Q. Q. How is Affytericin-B Injection administered??
    Ans: Affytericin-B Injection is either administered as intravenous injection or infusion by a registered medical professional only
  • Q. Q. How does Affytericin-B Injection cause nephrotoxicity and hyperkalemia??
    Ans: Affytericin-B Injection can disrupt the lipid components of human kidney cells, thereby causing nephrotoxicity. The exact mechanism of hypokalemia is not known, but kidney damage may result in excessive loss of potassium in urine.

FDC Ltd | B-8, MIDC Area, Waluj - 431 136, Dist. Aurangabad, Maharashtra


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References

FDA approved prescribing information. Levocitrizine; 1995 [revised May 2007]. [Accessed 01 Apr. 2019] (online) Available from: Read More

European Medicne Agency. Revised assessment report: Ambroxol and bromhexine containing medicinal products. 2015. [Accessed 01 Apr. 2019] (online) Available from: Read More

ScienceDirect. Ambroxol. [Accessed 01 Apr. 2019] (online) Available from: Read More

Levocitrizine. Slough, Berkshire: UCB Pharma Limited; 2007 [revised 27 Mar. 2019]. [Accessed 01 Apr. 2019] (online) Available from: Read More



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